Mannitol yog qab zib cawv nrog cov tshuaj formula C6H14O6. Nws yog yooj yim soluble nyob rau hauv dej thiab yog ib tug dawb crystalline hmoov nrog ib tug qab zib saj zoo li sucrose. Nws yog lub siab osmotic siab dehydrating tus neeg saib xyuas feem ntau siv hauv kev kho mob kom txo qis intracranial siab, txo lub hlwb edema, thiab txo cov ntshav viscosity hauv cov neeg mob.
Nws yog dav siv nyob rau hauv ntau lub teb xws li cov hauv qab no:
Mannitol feem ntau yog siv los kho lub hlwb edema los ntawm ntau yam laj thawj, thiab tiv thaiv lub hlwb herniation los ntawm kev txo qis intracranial siab. Tsis tas li ntawd, mannitol kuj tseem muaj cov txiaj ntsig ntawm kev txo qis intraocular siab thiab tuaj yeem siv los kho cov kab mob nrog siab siab intraocular siab. Nws tseem tuaj yeem siv los ua osmotic diuretic kom paub qhov txawv ntawm oliguria tshwm sim los ntawm lub raum ua ntej lossis mob raum tsis ua haujlwm, thiab tiv thaiv tus mob tubular necrosis. Mannitol kuj tseem siv los ua ib qho kev kho diuretic rau cov kab mob xws li nephrotic syndrome, cirrhosis, thiab ascites. Nws yuav tsum raug sau tseg tias kev txhaj tshuaj mannitol tuaj yeem siv tau tom qab crystallization, tab sis cov muaju yuav tsum tau yaj ua ntej, thiab nws yog contraindicated rau cov neeg uas tsis haum rau mannitol los tiv thaiv kev tsis haum tshuaj.
Muaj qee qhov kev ceev faj ua raws thaum siv mannitol. Ua ntej, kev txhaj tshuaj mannitol yog nquag crystallization ntawm qhov kub thiab txias, yog li cov muaju yuav tsum tau yaj tag ua ntej siv. Qhov thib ob, mannitol feem ntau yog siv rau kev txhaj tshuaj rau hauv cov hlab ntsha thiab tsis pom zoo rau kev siv qhov ncauj tshwj tsis yog tias nws yog siv los ua tus neeg ua haujlwm ua ntej lossis ua ntej kuaj plab hnyuv. Thaum kawg, cov neeg mob yuav tsum ua raws li tus kws kho mob cov lus qhia txog kev siv tshuaj thiab tsis txhob siv qhov muag tsis pom kev, tshwj xeeb tshaj yog rau cov neeg mob uas muaj mob qog nqaij hlav, lub cev qhuav dej, thiab lwm yam.
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Feature ntawmCrystalized mannitol:
- Crystalline mannitol yog cov hmoov dawb crystalline uas yooj yim soluble hauv dej, muaj qab zib saj, absorbs tshav kub thaum yaj, thiab tsis muaj hygroscopicity. Nws yog ib qho isomer ntawm sorbitol, ib txoj hlua ncaj nraim alkyl cawv uas muaj rau 6 pawg hydroxyl, feem ntau siv los ua ib daim ntawv racemic.
- Crystalline mannitol yog nquag tsim cov muaju nyob rau hauv chav tsev kub tsawg, tab sis cov muaju yuav yaj ntawm lawv tus kheej thaum sab laug ntawm chav tsev kub lossis cua sov.
- Mannitol muaj ntau yam kev siv. Raws li lub siab osmotic siab dehydrating tus neeg saib xyuas, nws yog feem ntau siv nyob rau hauv kev kho mob xyaum los txo intracranial siab, alleviate hlwb edema, alleviate neurological puas, thiab txo cov ntshav viscosity nyob rau hauv cov neeg mob. Tsis tas li ntawd, nws tseem tuaj yeem ua cov pa oxygen dawb radical scavenger, tshem tawm qhov nce ntawm cov pa dawb radicals los ntawm aseptic o ntawm cov ntaub so ntswg nyob ib puag ncig ntawm cov hlab ntsha hauv tus txha caj qaum, txo qhov kev puas tsuaj ntawm cov pa oxygen dawb radicals rau cell membranes, thiab ua lub luag haujlwm hauv kev txo qhov o thiab tiv thaiv inflammatory teebmeem.
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Specification ntawmCrystalized mannitol:
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TEM |
STANDARD |
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TSEEM CEEB |
Dawb crystalline hmoov |
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Assay |
98.0~102.0 % |
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Tsawg dua ntawm ziab |
Tsawg dua lossis sib npaug rau 0.5 % |
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Kev sib hloov kho qhov muag tshwj xeeb |
+137~+145 |
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Acidity |
Dhau qhov kev xeem |
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Hlawv residue |
Tsawg dua lossis sib npaug rau 0.1 % |
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Txo qab zib |
Dhau qhov kev xeem |
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Chloride |
Tsawg dua lossis sib npaug rau 0.003 % |
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Sulfate |
Tsawg dua lossis sib npaug rau 0.01 % |
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Oxalate |
Tsawg dua lossis sib npaug rau 0.02 % |
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Cov hlau hnyav |
Tsawg dua lossis sib npaug rau 0.001 % |
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Arsenic |
Tsawg dua lossis sib npaug rau 0.0002 % |
Kev tsim tawm ntawmCrystalized mannitol:
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Cim npe nrov: Tuam Tshoj crystalized mannitol manufacturers, lwm tus neeg, Hoobkas